You might be taking one of these if you have a heart rhythm condition, like atrial fibrillation.
Heart rhythm medications ( antiarrhythmics) can also interact with digoxin. Let your healthcare provider know right away if these develop during treatment. But they’re also common signs of digoxin toxicity. Nausea, vomiting, and diarrhea are common antibiotic side effects. Make sure your healthcare provider knows you’re taking digoxin before starting any antibiotic. It’s often referred to as a “Z-Pak.” Azithromycin can increase digoxin levels, but it’s unclear by how much.
Sulfamethoxazole/trimethoprim (Bactrim DS)Īnother common antibiotic that might interact with digoxin is azithromycin (Zithromax). Some examples of these antibiotics include: In some cases, blood levels can be 100% higher than normal. But mixing digoxin with certain antibiotics can cause your digoxin levels to get too high. Certain antibioticsĪntibiotics are medications that help treat or prevent bacterial infections. They can identify any others that may affect you. Share your current medication list with your healthcare provider and pharmacist. Below, we list several interactions that are common or more serious. Regular monitoring is done to ensure you stay in a safe range.īecause of this, it’s important to know about interactions that can affect your digoxin levels. And lower levels can prevent it from working as well. Higher digoxin levels can mean more side effects, including digoxin toxicity.
In other words, a small change in your digoxin levels can make a big difference in how well it works. This means the level of medication in your blood must remain within a small window. Digoxin interactions to know aboutĭigoxin is a narrow therapeutic index medication. And managing drug interactions is one way to prevent side effects from becoming worse. Regular blood monitoring helps ensure you’re taking the right dosage. And it can interact with a number of medications, too.Įven so, your healthcare provider may decide digoxin is the best option for you. But why?ĭigoxin can cause serious side effects, even at typical doses. Even though it has been around for a long time, it’s now being used less often. Never just stop taking blood pressure medication.Digoxin (Lanoxin) has been used to treat heart problems since it was first approved in the mid-1950s. National Library of Medicine: MedlinePlus. Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a systematic, multinational, large-scale analysis. Suchard MA, Schuemie MJ, Krumholz HM, et al. Patients’ decisions about whether or not to take antihypertensive drugs: qualitative study. Aging, arterial stiffness, and hypertension. Withdrawal of antihypertensive medication. Van der Wardt V, Harrison JK, Welsh T, Conroy S, Gladman J. Journal of Family Medicine and Primary Care. Resistant hypertension: An approach to management in primary care. Journal of the American College of Cardiology. 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA guideline for the prevention, detection, evaluation, and management of high blood pressure in adults.
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